In a study published recently, doctors from the PGIMER established the role of vitamin D supplement in achieving SARS-CoV-2 RNA negativity among Covid patients.
The study titled ‘Short term, high-dose vitamin D supplementation for Covid-19 disease’ was carried out by Dr Ashu Rastogi, Dr Anil Bhansali, Dr Niranjan Khare, Dr Vikas Suri, Dr Narayana Yaddanapudi, Dr Naresh Sachdeva, Dr GD Puri and Dr Pankaj Malhotra.
More so resembling a hormone, vitamin D is not technically a vitamin. Our bodies do not produce it on their own and it can only be processed through consuming specific foods, such as fatty fish, egg yolks, and fortified dairy products, and synthesised through our skin with direct exposure to sunlight—UVB rays specifically.
Its ability to assist in calcium absorption for good bone health is only one of its many critical biological benefits. “It’s not a panacea, but vitamin D seems to be essential for nearly all organ systems of the body,” says JoAnn Manson, a professor of epidemiology at Harvard’s T. P. Chan School of Public Health.
Low vitamin D levels have also been connected to depression, anxiety, cardiovascular function, and neurodegenerative disorders. But most recently, the ‘sunshine vitamin’ has been making headlines for something else: its role in possibly preventing and treating Covid-19.
“It’s critical to a healthy immune system,” says Manson. “But beyond that, vitamin D seems to have a benefit in tamping down the inflammation that can occur with Covid, and it may also have a role in reducing the risk of developing severe illness and a need for hospitalisation.”
Vitamin D3 supplements doesn’t benefit severe Covid-19 patients
However, a team of researchers at the University of São Paulo in Brazil found that vitamin D3 supplementation is ineffective in improving hospital length of stay or any other clinical outcomes among hospitalised patients with severe Covid-19.
The researchers intended to find whether vitamin D3 supplementation could help in the reduction of hospital duration for severe Covid-19 patients.
For the study, published in the journal medRxiv*, the team conducted a multi-centre, double-blind, randomised and placebo-controlled trial in two centres. They analysed 240 critically ill Covid-19 hospitalised patients.
According to World Health Organisation (WHO), “Micronutrients, such as vitamins D and C and zinc, are critical for a well-functioning immune system and play a vital role in promoting health and nutritional well-being. There is currently no guidance on the use of micronutrients supplements as a treatment of Covid-19.”
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